153096-83-4

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 153096-71-0 (S)-3,4-Bis-benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-butan-2-one 

Downstream Products

• 153096-70-9 (2S,3R)-1,2-Bis-benzyloxy-3-(tert-butyl-diphenyl-silanyloxymethyl)-pentan-3-ol 
• 153096-78-7 (2R,3S)-3,4-Bis-benzyloxy-2-ethyl-butane-1,2-diol 
• 370593-06-9 (3R,4S)-4,5-bis(benzyloxy)-3(tert-butyldiphenylsilyloxymethyl)-3-hydroxypentanenitrile 
• 370593-08-1 (4R)-4-[(1S)-1,2-bis(benzyloxy)ethyl]-4-hydroxytetrahydrofuran-2-one 
• 153096-81-2 (R)-2-((S)-1,2-Bis-benzyloxy-ethyl)-but-3-ene-1,2-diol 

Relevant academic research and scientific papers

Highly diastereoselective additions of organometallic reagents to 1-O-silylated 3,4-di-O-benzyl-L-erythrulose derivatives

The diastereoselectivity of the addition of several organometallic reagents to the carbonyl group of the title compounds has been investigated. Some organomagnesium reagents display high diastereoselectivities (90-99%) and the major products are those predicted by the α-chelation model.

Diastereoselectivity in Organometallic Additions to the Carbonyl Group of Protected Erythrulose Derivatives

We have investigated a number of nucleophillic additions to L-erythrulose derivatives (4-12) bearing protective O-silyl, O-benzyl, and O-trityl groups in various relative positions. The results are discussed in the frame of chelated vs nonchelated transit