Highly diastereoselective additions of organometallic reagents to 1-O-silylated 3,4-di-O-benzyl-L-erythrulose derivatives

Article abstract of DOI:10.1016/S0957-4166(00)80421-8

The diastereoselectivity of the addition of several organometallic reagents to the carbonyl group of the title compounds has been investigated. Some organomagnesium reagents display high diastereoselectivities (90-99%) and the major products are those predicted by the α-chelation model.