153142-44-0Relevant academic research and scientific papers
The Synthesis of Electron Donor-acceptor Substituted Pyrazoles
Miller, R. D.,Reiser, O.
, p. 755 - 764 (2007/10/02)
A variety of 1,3- and 1,5-donor-acceptor substituted pyrazole derivatives have been synthesized by the cyclocondensation of α,β-ethynyl ketones with substituted phenyl hydrazines.The regioselectivity of the cyclization depends on the reaction conditions in a manner consistent with competitive 1,2- and 1,4-addition followed by ring closure. 1,4-disubstituted derivatives can be prepared from the corresponding 4-iodopyrazole using palladium catalyzed carbon-carbon bond forming reactions.The pyrazole chromophores are expected to show interesting nonlinear optical properties.
