153153-72-1

Upstream product

• 153052-69-8 (2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-4-methyl-2-(methylamino)pentanoate 
• 153052-71-2 Boc-L-MeLeu-D-PhLac-OH 
• 153052-70-1 benzyl N-Boc-N-methyl-L-leucyl-3-phenyl-D-lactate 
• 153052-68-7 (2R)-1-(benzyloxy)-1-oxopropan-2-yl (2S)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoate 
• 53363-89-6 N-t-butoxycarbonyl-N-methyl-L-leucine 
• 2051-96-9 benzyl (R)-Lactate 
• 7622-21-1 (R)-benzyl mandelate 

Downstream Products

• 259093-42-0 C₅₀H₇₆N₆O₁₃ 
• 259093-41-9 C₅₇H₈₂N₆O₁₃ 
• 259093-40-8 C₆₂H₉₀N₆O₁₅ 
• 133413-70-4 8,20-dibenzyl-5,11,17,23-tetraisobutyl-2,4,10,14,16,22-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraaza-cyclotetracosan-3,6,9,12,15,18,21,24-octaone 
• 153052-74-5 benzyl N-Boc-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactate 
• 160518-08-1 benzyl N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactate 
• 153052-77-8 N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactic acid 
• 133413-70-4 PF1022A antipode 
• 153052-72-3 N-Boc-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactic acid 
• 153052-73-4 benzyl N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactate 

Relevant academic research and scientific papers

Azadepsipeptides: Synthesis and evaluation of a novel class of peptidomimetics

A general route to azadepsipeptides, a new class of pseudopeptides, has been established. The methodology was applied to the synthesis of a bis-aza analogue of the antiparasitic cyclooctadepsipeptide PF1022A. Comparison of the X-ray crystal structures of natural PF1022A (8) and the chimeric aza analogue 9 revealed that the introduction of nitrogen in the backbone of PF1022A results in almost complete conservation of the 3D structure with only minor deviations at the new nitrogen positions.