153168-59-3

Basic information

• Product Name: 2,6-dimethyl-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol
• Synonyms: 2,6-dimethyl-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol
• CAS NO: 153168-59-3
• Molecular Formula: C₁₁H₉F₃N₂O₂
• Molecular Weight: 258.2
• Mol File: 153168-59-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-dimethyl-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol(153168-59-3)
• EPA Substance Registry System: 2,6-dimethyl-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol(153168-59-3)

Safety Data

• Hazardous Substances Data: 153168-59-3(Hazardous Substances Data)

Usage

General Description

2,6-dimethyl-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol is a chemical compound with a complex structure. It consists of a phenol ring with two methyl groups and a 1,2,4-oxadiazole ring attached to it. The oxadiazole ring contains a trifluoromethyl group and is substituted at the 5-position. This chemical has potential uses in pharmaceuticals, agrochemicals, and material science due to its unique structure and properties. It may have applications in the development of new drugs, pesticides, or materials with specific functional characteristics. Further research is needed to fully understand the potential uses and effects of this compound.

Upstream product

• 4198-90-7 3,5-dimethyl-4-hydroxybenzonitrile 
• 407-25-0 trifluoroacetic anhydride 
• 162854-15-1 N',4-dihydroxy-3,5-dimethylbenzimidamide 

Downstream Products

• 174523-36-5 3-[4-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-butyl]-pyridine 
• 174523-32-1 2-methoxy-5-[3-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-propyl]-pyridine 
• 174523-69-4 3-[3-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-propyl]-quinoline 
• 174523-35-4 2-acetyl-6-[3-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-propyl]-pyridine 
• 174523-29-6 2-fluoro-5-[3-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-propyl]-pyridine 
• 174523-30-9 2-chloro-5-[3-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-propyl]-pyridine 
• 162854-24-2 6-methyl-3-[3-[4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenoxy]-propyl]-pyridine 

Relevant articles and documents

OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF

The present invention provides an anti-Coxsackie virus oxadiazole compound as represented by formula (I), or the pharmaceutically acceptable salt thereof, a preparation method, a pharmaceutical composition, and use thereof, wherein R is CH3 or CF3; R' and R are respectively H, alkyl or halogen; A is O or S; n is a number from 1 to 6; X is O, S or NH; Y is alkyl, unsubstituted cycloalkyl, mono-substituted cycloalkyl, disubstituted cycloalkyl, poly-substituted cycloalkyl, unsubstituted aryl, mono-substituted aryl, disubstituted aryl, poly-substituted aryl, unsubstituted 5-6 membered heterocyclyl, mono-substituted 5-6 membered heterocyclyl, disubstituted 5-6 membered heterocyclyl, or poly-substituted 5-6 membered heterocyclyl. Compared to prior art, the oxadiazole compound of the present invention has excellent anti-Coxsackie virus activity, lower toxicity and high safety.

1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS

Compounds of the formula wherein: R1 is alkyl, alkoxy, hydroxy, cycloalkyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkoxy, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxycarbonyl, carboxy, or cyanomethyl; Y is alkylene of 3 to 9 carbon atoms, R2 and R3 independently are hydrogen, alkyl, alkoxy, halo, cyano, trifluoromethyl and nitro; R4 is alkoxy, hydroxy, halomethyl, dihalomethyl, trihalomethyl, dihaloethyl, cycloalkyl, heterocyclyl, alkoxycarbonyl, hydroxyalkyl, alkoxyalkyl, alkanecarbonyloxyalkyl, cyano, halo, thioalkyl, alkylthioalkyl, alkylthio, thio, 2,2,2-trifluoro-ethyl, (4-methylphenyl)sulfonyloxymethyl, N=Q or CON=Q, where N=Q is amino, alkylamino or dialkylamino; R5 is hydrogen or halo or alkyl