153181-50-1 Usage
General Description
The chemical compound "(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(2-methylpropyl)-1,3-diazepan-2-one" is a complex organic compound with a diazepane ring structure. It contains two benzyl groups, two hydroxyl groups, and two 2-methylpropyl groups. The arrangement of atoms in the compound is such that it has four chiral centers, leading to a total of 16 possible stereoisomers. (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(2-methylpropyl)-1,3-diazepan-2-one likely has pharmaceutical or biological significance due to its complex structure and the presence of functional groups that are commonly found in bioactive molecules, although further information would be needed to fully understand its properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 153181-50-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,8 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 153181-50:
(8*1)+(7*5)+(6*3)+(5*1)+(4*8)+(3*1)+(2*5)+(1*0)=111
111 % 10 = 1
So 153181-50-1 is a valid CAS Registry Number.
153181-50-1Relevant articles and documents
Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
Lam, Patrick Y. S.,Ru, Yu,Jadhav, Prabhakar K.,Aldrich, Paul E.,DeLucca, George V.,Eyermann, Charles J.,Chang, Chong-Hwan,Emmett, George,Holler, Edward R.,Daneker, Wayne F.,Li, Liangzhu,Confalone, Pat N.,McHugh, Robert J.,Han, Qi,Li, Renhua,Markwalder, Jay A.,Seitz, Steven P.,Sharpe, Thomas R.,Bacheler, Lee T.,Rayner, Marlene M.,Klabe, Ronald M.,Shum, Linyee,Winslow, Dean L.,Kornhauser, David M.,Jackson, David A.,Erickson-Viitanen, Susan,Hodge, C. Nicholas
, p. 3514 - 3525 (2007/10/03)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking
