153182-52-6 Usage
General Description
The chemical compound "(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-methylbenzyl)-1,3-diazepan-2-one" is an organic compound with a complex molecular structure. It contains two benzyl groups, two hydroxyl groups, and an intricate diazepan ring with methylbenzyl substituents. (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(3-methylbenzyl)-1,3-diazepan-2-one belongs to the class of diazepane derivatives, which are known for their potential biological activities and pharmaceutical applications. The specific stereochemistry and functional groups in this compound could potentially provide unique properties and potential uses in drug discovery and medicinal chemistry. The compound may have potential applications in drug development, particularly in the field of neuropharmacology or as a potential therapeutic agent for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 153182-52-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,8 and 2 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 153182-52:
(8*1)+(7*5)+(6*3)+(5*1)+(4*8)+(3*2)+(2*5)+(1*2)=116
116 % 10 = 6
So 153182-52-6 is a valid CAS Registry Number.
153182-52-6Relevant articles and documents
Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
Lam, Patrick Y. S.,Ru, Yu,Jadhav, Prabhakar K.,Aldrich, Paul E.,DeLucca, George V.,Eyermann, Charles J.,Chang, Chong-Hwan,Emmett, George,Holler, Edward R.,Daneker, Wayne F.,Li, Liangzhu,Confalone, Pat N.,McHugh, Robert J.,Han, Qi,Li, Renhua,Markwalder, Jay A.,Seitz, Steven P.,Sharpe, Thomas R.,Bacheler, Lee T.,Rayner, Marlene M.,Klabe, Ronald M.,Shum, Linyee,Winslow, Dean L.,Kornhauser, David M.,Jackson, David A.,Erickson-Viitanen, Susan,Hodge, C. Nicholas
, p. 3514 - 3525 (2007/10/03)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking