153182-54-8

Basic information

• Product Name: (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(4-chlorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one
• Synonyms: 2H-1,3-Diazepin-2-one, 1,3-bis((4-chlorophenyl)methyl)hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-, (4R,5S,6S,7R)-; 2H-1,3-diazepin-2-one, 1,3-bis[(4-chlorophenyl)methyl]hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-, (4R,5S,6S,7R)-
• CAS NO: 153182-54-8
• Molecular Formula: C₃₃H₃₂Cl₂N₂O₃
• Molecular Weight: 575.5248
• Mol File: 153182-54-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 734.6°C at 760 mmHg
• Flash Point: 398.1°C
• Density: 1.326g/cm³
• Vapor Pressure: 1.18E-22mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(4-chlorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(4-chlorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one(153182-54-8)
• EPA Substance Registry System: (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(4-chlorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one(153182-54-8)

Safety Data

• Hazardous Substances Data: 153182-54-8(Hazardous Substances Data)

Usage

General Description

The chemical compound (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(4-chlorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one is a complex organic molecule with multiple benzyl and chlorobenzyl groups attached to a diazepan ring structure. The compound also contains two hydroxyl groups, contributing to its dihydroxy functionality. (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(4-chlorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one has potential applications in medicinal chemistry, particularly in drug discovery and development due to its unique structural features and potential biological activity. Further research and testing are needed to fully understand the properties and potential uses of this chemical.

Upstream product

• 63219-70-5 N-(benzyloxycarbonyl)-D-phenylalaninal 
• 183814-19-9 ((1S,2R,3S,4R)-1-Benzyl-4-benzyloxycarbonylamino-2,3-dihydroxy-5-phenyl-pentyl)-carbamic acid benzyl ester 
• 153181-22-7 (4R,5S,6S,7R)-hexahydro-5,6-bis[2-(trimethylsilyl)ethoxymethoxy]-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-one 
• 58917-85-4 N-(benzyloxycarbonyl)-D-phenylalaninol 

Relevant articles and documents

Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas

High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking