153182-63-9 Usage
General Description
The chemical (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(2-ethoxyethyl)-5,6-dihydroxy-1,3-diazepan-2-one is a complex organic compound with a unique molecular structure. It contains two benzyl groups, two ethoxyethyl groups, and two hydroxy groups. The presence of a diazepan ring in its structure gives it potential pharmacological applications, as diazepan is a common structural motif in pharmaceutical compounds. The compound's stereochemistry is also defined by the (4R,5S,6S,7R) configuration, indicating its specific 3D arrangement of atoms. Due to its complex nature and potential pharmacological activity, this chemical may be of interest to researchers in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 153182-63-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,8 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 153182-63:
(8*1)+(7*5)+(6*3)+(5*1)+(4*8)+(3*2)+(2*6)+(1*3)=119
119 % 10 = 9
So 153182-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C27H38N2O5/c1-3-33-17-15-28-23(19-21-11-7-5-8-12-21)25(30)26(31)24(20-22-13-9-6-10-14-22)29(27(28)32)16-18-34-4-2/h5-14,23-26,30-31H,3-4,15-20H2,1-2H3/t23-,24-,25+,26+/m1/s1
153182-63-9Relevant articles and documents
Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
Lam, Patrick Y. S.,Ru, Yu,Jadhav, Prabhakar K.,Aldrich, Paul E.,DeLucca, George V.,Eyermann, Charles J.,Chang, Chong-Hwan,Emmett, George,Holler, Edward R.,Daneker, Wayne F.,Li, Liangzhu,Confalone, Pat N.,McHugh, Robert J.,Han, Qi,Li, Renhua,Markwalder, Jay A.,Seitz, Steven P.,Sharpe, Thomas R.,Bacheler, Lee T.,Rayner, Marlene M.,Klabe, Ronald M.,Shum, Linyee,Winslow, Dean L.,Kornhauser, David M.,Jackson, David A.,Erickson-Viitanen, Susan,Hodge, C. Nicholas
, p. 3514 - 3525 (2007/10/03)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking