153183-11-0 Usage
General Description
The chemical "(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[3-(hydroxymethyl)benzyl]-1,3-diazepan-2-one" is a complex compound with a diazepane ring structure. It contains multiple benzyl and hydroxymethyl groups attached to the diazepane ring, as well as two hydroxyl groups. The compound has a total of seven chiral centers, giving rise to numerous stereoisomers. This chemical may have potential biological or pharmacological applications due to its complex structure and potential interactions with biological systems. However, further research is needed to fully understand and elucidate its properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 153183-11-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,8 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153183-11:
(8*1)+(7*5)+(6*3)+(5*1)+(4*8)+(3*3)+(2*1)+(1*1)=110
110 % 10 = 0
So 153183-11-0 is a valid CAS Registry Number.
153183-11-0Relevant articles and documents
Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
Lam, Patrick Y. S.,Ru, Yu,Jadhav, Prabhakar K.,Aldrich, Paul E.,DeLucca, George V.,Eyermann, Charles J.,Chang, Chong-Hwan,Emmett, George,Holler, Edward R.,Daneker, Wayne F.,Li, Liangzhu,Confalone, Pat N.,McHugh, Robert J.,Han, Qi,Li, Renhua,Markwalder, Jay A.,Seitz, Steven P.,Sharpe, Thomas R.,Bacheler, Lee T.,Rayner, Marlene M.,Klabe, Ronald M.,Shum, Linyee,Winslow, Dean L.,Kornhauser, David M.,Jackson, David A.,Erickson-Viitanen, Susan,Hodge, C. Nicholas
, p. 3514 - 3525 (2007/10/03)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking
