153183-24-5 Usage
Uses
Used in Pharmaceutical Industry:
(4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclobutylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one is used as a potential pharmaceutical candidate due to its unique structural features and stereochemistry. The presence of the diazepane ring, benzyl and cyclobutylmethyl substituents, and hydroxyl groups may confer specific biological activities that can be harnessed for the development of new drugs.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclobutylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one serves as a target compound for studying its potential interactions with biological targets and its effects on various biological pathways. Understanding these interactions can lead to the discovery of new therapeutic agents and the optimization of the compound's pharmacological properties.
Used in Synthetic Organic Chemistry:
(4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclobutylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one is also utilized in synthetic organic chemistry as a model compound for developing new synthetic routes and methodologies. The synthesis of this complex molecule with multiple stereocenters presents a challenge that can drive innovation in the field, potentially leading to more efficient and selective synthetic processes.
Check Digit Verification of cas no
The CAS Registry Mumber 153183-24-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,8 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 153183-24:
(8*1)+(7*5)+(6*3)+(5*1)+(4*8)+(3*3)+(2*2)+(1*4)=115
115 % 10 = 5
So 153183-24-5 is a valid CAS Registry Number.
InChI:InChI=1/C29H38N2O3/c32-27-25(17-21-9-3-1-4-10-21)30(19-23-13-7-14-23)29(34)31(20-24-15-8-16-24)26(28(27)33)18-22-11-5-2-6-12-22/h1-6,9-12,23-28,32-33H,7-8,13-20H2/t25-,26-,27+,28+/m1/s1
153183-24-5Relevant academic research and scientific papers
Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
Lam, Patrick Y. S.,Ru, Yu,Jadhav, Prabhakar K.,Aldrich, Paul E.,DeLucca, George V.,Eyermann, Charles J.,Chang, Chong-Hwan,Emmett, George,Holler, Edward R.,Daneker, Wayne F.,Li, Liangzhu,Confalone, Pat N.,McHugh, Robert J.,Han, Qi,Li, Renhua,Markwalder, Jay A.,Seitz, Steven P.,Sharpe, Thomas R.,Bacheler, Lee T.,Rayner, Marlene M.,Klabe, Ronald M.,Shum, Linyee,Winslow, Dean L.,Kornhauser, David M.,Jackson, David A.,Erickson-Viitanen, Susan,Hodge, C. Nicholas
, p. 3514 - 3525 (2007/10/03)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking
