153184-04-4Relevant academic research and scientific papers
Lateral lithiation in deep eutectic solvents: regioselective functionalization of substituted toluene derivatives
Arnodo, Davide,Blangetti, Marco,Ghinato, Simone,Nejrotti, Stefano,Prandi, Cristina
supporting information, p. 2391 - 2394 (2020/03/06)
The heteroatom-directed lateral lithiation of functionalized toluenes in a choline chloride-based eutectic mixture is reported. The metalations proceed within ultrafast reaction times, with a broad substrate and electrophile scope. The directing groups pr
Directed lithiations: The effect of varying directing group orientation on competitive efficiencies for a series of tertiary amide, secondary amide, and alkoxide directed ortho lithiations
Beak, Peter,Kerrick, Shawn T.,Gallagher, Donald J.
, p. 10628 - 10636 (2007/10/02)
Significant differences for competitive efficiencies in directed ortho lithiations for single functional groups in three series, the secondary benzamides 1-4, the tertiary benzamides 5-11, and the benzylic alcohols 12-17, are reported. For both amide seri
