153199-54-3

Basic information

• Product Name: 3-Pyridinol,4-methoxy-(9CI)
• Synonyms: 3-Pyridinol,4-methoxy-(9CI);3-Hydroxy-4-methoxypyridine;4-Methoxy-3-hydroxypyridine;4-methoxy-3-Pyridinol
• CAS NO: 153199-54-3
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125.13
• EINECS: 604-604-1
• Product Categories: PYRIDINE
• Mol File: 153199-54-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 326.104 °C at 760 mmHg
• Flash Point: 151.023 °C
• Appearance: /
• Density: 1.191 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.44±0.18(Predicted)
• CAS DataBase Reference: 3-Pyridinol,4-methoxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinol,4-methoxy-(9CI)(153199-54-3)
• EPA Substance Registry System: 3-Pyridinol,4-methoxy-(9CI)(153199-54-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 153199-54-3(Hazardous Substances Data)

Usage

General Description

3-Pyridinol,4-methoxy-(9CI) is a chemical compound with the molecular formula C6H7NO2. It is a derivative of pyridine with a methoxy group attached to the fourth carbon atom. 3-Pyridinol,4-methoxy-(9CI) is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceuticals. It has also been studied for its potential use in the treatment of neurological disorders and as a precursor in the synthesis of agrochemicals. 3-Pyridinol,4-methoxy-(9CI) is a versatile compound with a range of potential applications in the fields of medicine, agriculture, and chemical synthesis.

InChI:InChI=1/C6H7NO2/c1-9-6-2-3-7-4-5(6)8/h2-4,8H,1H3

Upstream product

• 210300-15-5 4-methoxy-3-methoxymethoxypyridine 
• 1122-96-9 4-methoxypyridine N-oxide 
• 620-08-6 4-methoxypyridine 

Downstream Products

• 109613-93-6 3,4-dimethoxypyridine 
• 332134-00-6 2-benzyl-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidine-1-yl]pyridine 
• 107512-35-6 3,4-dimethoxy-2-methylpyridine 
• 104819-52-5 2-bromo-3,4-dimethoxy pyridine 
• 101664-55-5 3,3',4,4'-tetramethoxy-2,2'-bipyridine 
• 220437-83-2 3,4-dimethoxypicolinic acid 
• 848773-53-5 1-[4-(4-methoxy-pyridin-3-yloxy)-phenyl]-5-oxo-pyrrolidine-2,2-dicarboxylic acid diethyl ester 

Relevant articles and documents

A concise approach towards the synthesis of WS75624 a and WS75624 B via the cross-metathesis of vinyl-functionalized thiazoles

Synthetic approach towards precursors of WS75624 A and WS75624 B, two potent endothelin converting enzyme (ECE) inhibitors and potential antihypertensive agents, is reported featuring a key cross-metathesis between a vinyl-functionalized thiazole and a terminal olefin. As the two natural products only differ by the nature of their hydroxyalkyl side-chain, our convergent strategy enable the synthesis of key intermediates of both molecules in a limited amount of steps.

New Synthesis of Orelline by Metalation of Methoxypyridines

A new total synthesis in five steps of alkaloid Orelline is reported.The methodology involves metalation of methoxypyridines to afford 2-halo-3,4-dimethoxypyridine on which an homocoupling reaction is performed to build the 2,2'-bipyridyl structure of the