153204-23-0Relevant academic research and scientific papers
Total asymmetric syntheses of (+)-blastmycinone and related γ-lactones
Nishide,Aramata,Kamanaka,Inoue,Node
, p. 8337 - 8346 (1994)
The freeze of the conformer was realized by the introduction of an alkyl substituent at α-position of tetronic acid using a readily available none C2 chiral auxiliary (SMP or RMP), and conducted the desired asymmetric γ- methylation. Its application to expeditious total syntheses of (+)- blastmycinone (1) and (-)-3-epi-blastmycinone (2), and to the first total synthesis of (+)-(3R,4R,5R)-4-acetoxy-5-methyl-3-tetradecyltetrahydro-2(5H)- furanone (3) was described.
An Expeditious Total Synthesis Of (+)-Blastmycinone
Nishide, Kiyoharu,Aramata, Atsunori,Kamanaka, Teruki,Node, Manabu
, p. 2237 - 2240 (2007/10/02)
Asymmetric γ-methylation of tetronic acid using (S)-2-methoxymethylpyrrolidine as a chiral auxiliary and its application to the total synthesis of (+)-blastmycinone (1) were described
