78128-80-0Relevant academic research and scientific papers
Synthesis of peroxylactones using Mn(III)-catalyzed aerobic oxidation
Haque, Md. Aminul,Nishino, Hiroshi
, p. 1783 - 1805 (2011/09/21)
The aerobic oxidation of tetronic acid in the presence of 1,1-disubstituted alkenes afforded hydroperoxyethyl-peroxylactones, while a similar reaction using 3-alkyl-substituted tetronic acids gave stable crystalline peroxylactones in good to excellent yields. The oxidation using a stoichiometric amount of manganese(III) acetate did not give the bicyclic lactone but the ethenyland/ or ethyl-tetronic acid derivatives. The Japan Institute of Heterocyclic Chemistry.
Total asymmetric syntheses of (+)-blastmycinone and related γ-lactones
Nishide,Aramata,Kamanaka,Inoue,Node
, p. 8337 - 8346 (2007/10/02)
The freeze of the conformer was realized by the introduction of an alkyl substituent at α-position of tetronic acid using a readily available none C2 chiral auxiliary (SMP or RMP), and conducted the desired asymmetric γ- methylation. Its application to expeditious total syntheses of (+)- blastmycinone (1) and (-)-3-epi-blastmycinone (2), and to the first total synthesis of (+)-(3R,4R,5R)-4-acetoxy-5-methyl-3-tetradecyltetrahydro-2(5H)- furanone (3) was described.
A convenient synthesis of 3-alkyltetronic acids from 3-acyltetronic acids
Sibi,Sorum,Bender,Gaboury
, p. 809 - 816 (2007/10/02)
Reductive deoxygenation of 3-acyltetronic acids provides 3-alkyltetronic acids in high yields under mild reaction conditions.
