153214-79-0

Upstream product

• 40166-30-1 3-(benzyloxy)-2,2-dimethoxypropan-1-ol 
• 154458-56-7 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-(phenylmethoxy)-2-propanol 
• 187397-77-9 2,5-bis(benzyloxymethyl)-2,5-diethoxy-1,4-dioxane 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 13071-59-5 3-benzyloxypropan-1,2-diol 
• 2930-05-4 Benzyloxymethyl-oxiran 
• 100-51-6 benzyl alcohol 

Downstream Products

• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 1253120-87-4 C₁₂H₁₆O₃ 
• 1610617-10-1 (R)-4-((benzyloxy)methyl)-4-vinyl-1,3-dioxolane 
• 1610616-88-0 4-((benzyloxy)methyl)-4-vinyl-1,3-dioxolan-2-one 
• 121787-44-8 (-)-1-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 151212-86-1 (+)-1-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 17325-86-9 (+)-(S)-1,2-di-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 87385-73-7 1-benzyloxy-3-acetoxypropan-2-one 

Relevant academic research and scientific papers

DIHYDROXYACETONE MONOETHERS

The present invention relates to the use of dihydroxyacetone monoethers as self-tanning substance, to preparations comprising dihydroxyacetone monoethers, and to certain dihydroxyacetone monoethers and to a process for the preparation thereof.

Microbial oxidation of 1,2-diols bearing a substituent with an oxyfunctional group: Preparation of optically active 1,2-diols and α-hydroxy ketones

The preparation of optically active 1,2-diols bearing a substituent with a benzyloxy group at the terminus has been achieved by microbial enantioselective oxidation of the racemic compounds. In the screening test, Ochrobactrum sp. MU2293 was selected as the best strain to perform the enantioselective oxidation of (±)-4-benzyloxybutane-1,2-diol to give the corresponding 4-benzyloxy-1-hydroxybutan-2-one and the remaining (R)-diol with a high ee. This microbial oxidation was applicable to other substrates bearing a substituent with a different carbon number. On the other hand, Bacillus sp. MU2289 catalyzed the oxidation of the 1,2-diols to afford the corresponding α-hydroxy ketones and the (S)-diols as the remaining substrates with the opposite absolute configuration.

Microbial asymmetric reduction of α-hydroxyketones in the anti-Prelog selectivity

Yamadazyma farinosa IFO 10896 was found to reduce α-hydroxyketones bearing a phenyl ring to give optically active diols with anti-Prelog selectivity. The distance between the carbonyl group and the phenyl ring was shown to have an interesting effect on the reactivity and selectivity of the enzyme system.

Baker's yeast mediated reduction of dihydroxyacetone derivatives

Several monoprotected dihydroxyacetone derivatives 4a-d and their acetates 5a-d were prepared and subjected to biotransformation with baker's yeast. The simple chemical modification of the substrates (i.e. transforming the relatively small hydrophilic hyd

Synthesis and Ruthenium-Catalyzed Enantioselective Hydrogenation of 3-O-Substituted 1,3-dihydroxypropan-2-ones

A number of 3-O-substituted 1,3-dihydroxypropan-2-ones have been synthesized in view of their potential use as prochiral precursors of optically active glycerols.Indeed, the oxo-ethers have been reduced to the corresponding 3-O-substituted glycerols via c