153229-38-0Relevant articles and documents
Stereocontrolled syntheses of C-aryl taxanes by intramolecular Heck olefination. Novel instances of diastereofacial guidance by proximal coordination
Young, Wendy B.,Masters, John J.,Danishefsky, Samuel
, p. 5228 - 5234 (2007/10/02)
Stereospecific syntheses of baccatin III constructs bearing an aromatic C-ring (2a and 2b) have been demonstrated. A key step involves the use of an intramolecular Heck olefination reaction to form the C10-C11 bond. Novel stereospeci
A CONCISE SYNTHESIS OF A HIGHLY FUNCTIONALIZED C-ARYL TAXOL ANALOG BY AN INTRAMOLECULAR HECK OLEFINATION REACTION
Masters, John J.,Jung, David K.,Bornmann, William G.,Danishefsky, Samuel J.,Gala, Susan de
, p. 7253 - 7256 (2007/10/02)
A palladium(O) catalyzed intramolecular Heck olefination used to establish the C10-C11 connection in a highly functionalized taxane analog is described.