1532592-34-9Relevant academic research and scientific papers
Asymmetric synthesis of N-stereogenic molecules: Diastereoselective double aza-Michael reaction
Lauber, Alex,Zelenay, Benjamin,Cvengros, Jan
, p. 1195 - 1197 (2014/02/14)
A novel approach towards the asymmetric synthesis of N-stereogenic molecules via double aza-Michael addition was developed. The diastereomeric ratio can be increased by a thermodynamically controlled isomerization mechanism. Simple separation and functionalization of the products afford N-stereogenic compounds in high enantiomeric purity.
