153277-55-5

Upstream product

• 110-62-3 pentanal 
• 188447-91-8 (S)-p-toluenesulfinimide 

Downstream Products

• 814256-30-9 methyl (S_S,S)-(+)-3-(p-toluenesulfinylamino)heptanoate 
• 503819-47-4 [1R,(S)S]-N-{[(S)-2-(p-toluenesulfinyl)benzyl]pentyl}-p-toluenesulfinamide 
• 503819-60-1 (1R)-1-{(S)-1-[(S)-2-(p-toluenesulfinyl)phenyl]ethyl}pentylamine 
• 503819-59-8 (1R)-1-{(S)-2-[p-toluenesulfinyl]benzyl}pentylamine 
• 503819-61-2 (1R)-1-[(S)-1-(phenyl)ethyl]pentylamine 
• 87982-83-0 (1R)-1-benzylpentylamine 
• 814256-33-2 dimethyl (S_S,S)-(+)-2-oxo-4-(p-toluenesulfinylamino)octylphosphonate 
• 503819-55-4 [1R,2S,(S)S]-N-{1-[(S)-(2-(p-toluenesulfinyl)phenyl)ethyl]pentyl}-p-toluenesulfinamide 
• 852332-94-6 [1R,2S,(S)S]-N-{1-butyl-2-[(S)-2-(p-toluenesulfinyl)phenyl]-2-(methylthio)ethyl}-p-toluenesulfinamide 

Relevant academic research and scientific papers

Facile synthesis of optically pure 1,2-diaryl (and 1-alkyl-2-aryl) ethyl and propylamines

(Figure presented) A concise high-yielding route to synthetically useful 1,2-diaryl (and 1-alkyl-2-aryl) ethyl and propylamines in high enantiomeric purity is described. The key step of this route is the completely stereoselective addition of lithium (R)-ortho-(p-toluenesulfinyl)benzylic carbanions to (S).N.p-toluenesulfinylimines, which takes place in very high or quantitative yields. N-Desulfinyiation and C-desulfinylation of the resulting adducts can be achieved with no loss of optical purity employing conventional methods (TFA and Raney-Ni, respectively).