15328-87-7Relevant articles and documents
Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells
Min, Garam,Lee, Su-Kyung,Kim, Hye-Nan,Han, Young-Min,Lee, Rhan-Hee,Jeong, Dae Gwin,Han, Dong Cho,Kwon, Byoung-Mog
, p. 3769 - 3774 (2013/07/27)
PRL-3, phosphatase of regenerating liver-3, plays a role in cancer progression through its involvement in invasion, migration, metastasis, and angiogenesis. We synthesized rhodanine derivatives, CG-707 and BR-1, which inhibited PRL-3 enzymatic activity wi
A solvent-free protocol for the green synthesis of arylalkylidene rhodanines in a task-specific ionic liquid
Alizadeh, Abdolhamid,Khodaei, Mohammad M.,Eshghi, Ali
experimental part, p. 514 - 518 (2010/08/04)
2-Hydroxyethylammonium formate acts as a task-specific ionic liquid (TSIL) for the Knoevenagel condensation of carbonyl compounds with rhodanine to afford arylalkylidene rhodanines under solvent-free conditions and in good-to-excellent yields. Additionally, compared with those in organic solvents, the yields obtained in the presence of our ionic liquid (IL) were significantly increased. The detailed mechanism of the catalytic effect of TSIL is also reported for the first time.