153283-46-6Relevant academic research and scientific papers
4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use
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, (2008/06/13)
Compounds of formula (I): [in which: R1 is hydrogen, alkyl, cycloalkyl or alkanoyl; R2 is a single bond, alkylene or alkylidene; R3 and R4 are each hydrogen or alkyl; R6 is carboxy or tetrazol-5-yl; and X is oxygen or sulphur]; and pharmaceutically acceptable salts and esters thereof are AII antagonists and can be used for the treatment and prophylaxis of hypertension and cardiovascular diseases.
