153294-01-0Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER
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Page/Page column 130, (2013/04/13)
The present invention provides MDM2 inhibitor compounds of Formula I or II, or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.
Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres
Uehling, David E.,Donaldson, Kelly H.,Deaton, David N.,Hyman, Clifton E.,Sugg, Elizabeth E.,Barrett, David G.,Hughes, Robert G.,Reitter, Barbara,Adkison, Kim K.,Lancaster, Mary E.,Lee, Frank,Hart, Robert,Paulik, Mark A.,Sherman, Bryan W.,True, Timothy,Cowan, Conrad
, p. 567 - 583 (2007/10/03)
Starting from phenethanolamine aniline leads 3a and 3b, we have identified a series of functionally potent and selective β3 adrenergic receptor (AR) agonists containing acylsulfonamide, sulfonylsulfonamide, or sulfonylurea groups within the ani