402509-08-4

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 104-03-0 4-nitrobenzeneacetic acid 
• 174891-00-0 methyl (2R)-2-{(tert-butoxycarbonyl)[(2R)-2-{[tert-butyl(dimethyl)silyl]oxy}-2-(3-chlorophenyl)ethyl]amino}propanoate 
• 104-84-7 para-methylbenzylamine 
• 349411-17-2 2-(4-nitrophenyl)-N-4-methylbenzylacetamide 
• 153294-01-0 methyl (2R)-{[tert-butyl(dimethyl)silyl]oxy}(3-chlorophenyl)ethanoate 
• 153294-00-9 (R)-3-chloromandelic acid methyl ester 
• 16273-37-3 (R)-3-chloromandelic acid 
• 402508-87-6 2-(4-aminophenyl)-N-4-methylbenzylacetamide 
• 174891-03-3 1,1-dimethylethyl ((2R)-2-(3-chlorophenyl)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}ethyl)[(1R)-1-methyl-2-oxoethyl]carbamate 

Relevant academic research and scientific papers

Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres

Starting from phenethanolamine aniline leads 3a and 3b, we have identified a series of functionally potent and selective β3 adrenergic receptor (AR) agonists containing acylsulfonamide, sulfonylsulfonamide, or sulfonylurea groups within the ani