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Usage

Uses

Used in Organic Synthesis:
BIS(4-ETHYNYLPHENYL)ACETYLENE is utilized as a key intermediate in organic synthesis for its ability to facilitate the formation of a variety of organic compounds. Its ethynyl and phenyl groups provide a versatile platform for further chemical reactions, enhancing the diversity of molecules that can be synthesized.
Used in Polymer Production:
In the polymer industry, BIS(4-ETHYNYLPHENYL)ACETYLENE serves as a crucial building block. Its incorporation into polymer structures contributes to the development of materials with specific properties tailored for various applications, such as high-strength plastics, adhesives, and coatings.
Used in Research Applications:
BIS(4-ETHYNYLPHENYL)ACETYLENE is extensively used in research settings to explore its chemical behavior and potential applications. Scientists leverage its unique properties to investigate new reaction pathways, develop novel synthetic methods, and understand its interactions with other molecules, thereby expanding the frontiers of chemical knowledge.
Used in Pharmaceutical Development:
Although not explicitly mentioned in the provided materials, given its role in organic synthesis and polymer production, BIS(4-ETHYNYLPHENYL)ACETYLENE could potentially be used in the pharmaceutical industry as a precursor for the development of new drug molecules or as a component in drug delivery systems, leveraging its ability to form complex molecular structures.

InChI:InChI=1/C18H10/c1-3-15-5-9-17(10-6-15)13-14-18-11-7-16(4-2)8-12-18/h1-2,5-12H

Upstream product

• 2789-89-1 1,2-bis(4-bromophenyl)acetylene 
• 190143-09-0 C₂₄H₂₂O₂ 
• 134856-58-9 1-iodo-4-(trimethylsilylethynyl)benzene 
• 66228-76-0 4-(trimethylsilylethynyl)phenylacetylene 
• 120517-37-5 4-(3-hydroxy-3-methyl-1-butynyl)-1-iodobenzene 
• 624-38-4 para-diiodobenzene 
• 886989-34-0 4-[(trimethylsilyl)ethynyl]-1-(3-hydroxyl-3-methylbutynyl)benzene 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 16116-78-2 (4-bromophenyl)(trimethylsilyl)acetylene 
• 589-87-7 1,4-bromoiodobenzene 
• 29619-42-9 1,1'-[ethyne-1,2-diylbis(4,1-phenylene)]diethanone 

Downstream Products

• 1031820-48-0 C₄₂H₂₆N₈ 
• 1190592-46-1 5,5'-[ethyn-1,2-diyl-bis(benzene-4,1-diyl-ethyn-2,1-diyl)]diuracil 
• 1215069-05-8 [Ru(II)Cl(CO)(PMe3)3]2(μ-CH=CH-C6H4CCC6H4-CH=CH) 
• 1196994-42-9 4,4'-bis((E)-dimesitylborylethenyl)tolan 

Relevant academic research and scientific papers

Direct Enzymatic Branch-End Extension of Glycocluster-Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity

The sequence of a glycan and its topology of presentation team up to determine the specificity and selectivity of recognition by saccharide receptors (lectins). Structure–activity analysis would be furthered if the glycan part of a glycocluster could be efficiently elaborated in situ while keeping all other parameters constant. By using a bacterial α2,6-sialyltransferase and a small library of bi- to tetravalent glycoclusters, we illustrate the complete conversion of scaffold-presented lactoside units into two different sialylated ligands based on N-acetyl/glycolyl-neuraminic acid incorporation. We assess the ensuing effect on their bioactivity for a plant toxin, and present an analysis of the noncovalent substrate binding contacts that the added sialic acid moiety makes to the lectin. Enzymatic diversification of a scaffold-presented glycan can thus be brought to completion in situ, offering a versatile perspective for rational glycocluster engineering.

2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective 'turn-on' fluorescent chemosensors for Ni(II)

A series of ethynylarene compounds containing 2-(1,2,3-triazol-4-yl)pyridine chelating units were studied as fluorescent chemosensors for metal cations in aqueous solution. Analogs possessing two chelating units bridged by either 1,4-diethynylphenyl or 2,7-diethynylnaphthyl subunits displayed large hypsochromic shifts coupled with signal intensification when exposed to increasing concentrations of Ni(II), a unique response among 22 metal cation analytes. This response was shown to be reversible, and is proposed to derive from disruption of aggregate formation upon Ni(II) binding at the peripheral chelating units.

Rigid rod and tetrahedral hybrid compounds featuring nucleobase and nucleoside End-capped structures

Being aimed at a new type of porous solids, a moduled design strategy of molecular tectons, making use of the conjugation between a shape defined artificial backbone and the bioinspired molecular fragments of nucleobases or nucleobase derivatives as functional end-caps, has been developed. This led to the formation of the new hybrid compounds 1-13 of linear and tetrahedral geometry, containing uracil, adenine, adenosine, guanosine and its acylated analogs as the sticky end-cap sites. The compounds were synthesized from a halogen or ethynyl substituted nucleobase component and the corresponding ethynylated spacer unit following a metal assisted coupling process as the key reaction step. X-Ray crystal structure analysis demonstrates that the parent compound 1 is a solvent complex with DMSO (1:2), showing the DMSO molecules incorporated in a hydrogen bonded layer structure. Specific dependencies of the fluorescence properties of the new compounds in solution on the structure of the molecules are reported. A selection of solid compounds has been studied in respect of their ability to adsorb organic vapours. They revealed significant differences both in the sorption capacity and the selectivity towards particular solvent vapours.

Organosilane compound and organosilica obtained therefrom

Provided is an organosilane compound expressed by any one of the following general formulae (1) to (7): (wherein: Ar represents a phenylene group or the like; R1 represents a hydrogen atom or the like; R2 to R8 each represent a methyl group or the like; n represents an integer in a range from 0 to 2; m represents an integer of 1 or 2; L represents a single bond or the like; X represents a hydrogen atom or the like; and Y represents a hydrogen atom or the like).

Synthesis of a giant 222 carbon graphite sheet

In this paper we present the synthesis and characterization of the so far largest polycyclic aromatic hydrocarbon (PAH), containing 222 carbon atoms or 37 separate benzene units. First a suitable three-dimensional oligophenylene precursor molecule is buil

ORGANOMETALLIC NLO-MATERIALS BASED ON ACETYL- AND ETHYNYLTOLANES AS RIGID ROD INTERMEDIATES

The synthesis of paraphenylene acetylenes is introduced, following a concept which makes a complete homologous series -(p-C6H4-CC)-n accessible.Systematic linkage with electroactive units leads to highly conjugated donor-acceptor systems.Organo