1533-53-5Relevant academic research and scientific papers
Rearrangement of 4-oxoalkane-1,1,2,2-tetracarbonitriles in the directed synthesis of aryl-substituted 2-(3-cyano-5-hydroxy-1,5-dihydro-2H-pyrrol-2-ylidene)malononitriles
Belikov, Mikhail Yu.,Fedoseev, Sergey V.,Ievlev, Mikhail Yu.,Ershov, Oleg V.
, p. 1057 - 1060 (2017)
[Figure not available: see fulltext.] 3-Aryl-4-oxoalkane-1,1,2,2-tetracarbonitriles were synthesized by the interaction of 2-aryl ketones with tetracyanoethylene. Directed rearrangement of them in acetic acid in the presence of ammonium acetate led to the
New approach to the synthesis of 2,3-dihydrofuro[2,3-b]pyridine derivatives: double reduction and double heterocyclization of 2-(3-cyano-5-hydroxy-1,5-dihydro-2H-pyrrol-2-ylidene)malononitriles in the presence of sodium borohydride
Belikov, Mikhail Yu.,Fedoseev, Sergey V.,Ievlev, Mikhail Yu.,Ershov, Oleg V.
, p. 447 - 450 (2018)
[Figure not available: see fulltext.] The reaction of 2-(3-cyano-5-hydroxy-1,5-dihydro-2H-pyrrol-2-ylidene)malononitriles with an excess of sodium borohydride resulted in diastereoselective formation of 2,3-diaryl-substituted 4,6-diamino-2,3-dihydrofuro[2,3-b]pyridine-5-carbonitriles. This process was accompanied by opening of the pyrrole ring in the starting compounds, followed by a double reduction and tandem closure of furan and pyridine rings.
Three-component synthesis of alkylammonium 4-cyano-5-(dicyanomethylene)-2-hydroxy-2,5-dihydropyrrol-1-ides
Fedoseev, Sergey V.,Belikov, Mikhail Yu.,Ievlev, Mikhail Yu.,Ershov, Oleg V.,Tafeenko, Viktor A.
, p. 3565 - 3579 (2018)
This study presents a three-component reaction between malononitrile dimer, α-diketone and aliphatic amine that leads to the formation of previously undescribed alkylammonium 4-cyano-5-(dicyanomethylene)-2-hydroxy-2,3-dimethyl-2,5-dihydropyrrol-1-ides. This reaction is a novel approach for modification of donor–acceptor chromophores containing the buta-1,3-diene-1,1,3-tricarbonitrile moiety.
