153312-38-0

Basic information

• Product Name: N-(4,6-DIMETHYL-2-PYRIMIDINYL)-4-NITROBENZENESULFONAMIDE
• Synonyms: N-(4,6-dimethylpyrimidin-2-yl)-4-nitrobenzenesulfonamide
• CAS NO: 153312-38-0
• Molecular Formula: C₁₂H₁₂N₄O₄S
• Molecular Weight: 308.3178
• Mol File: 153312-38-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 220-221 °C
• Boiling Point: 540.8°C at 760 mmHg
• Flash Point: 280.9°C
• Appearance: /
• Density: 1.472g/cm³
• Vapor Pressure: 9.24E-12mmHg at 25°C
• Refractive Index: 1.633
• PKA: 6.07±0.10(Predicted)
• CAS DataBase Reference: N-(4,6-DIMETHYL-2-PYRIMIDINYL)-4-NITROBENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4,6-DIMETHYL-2-PYRIMIDINYL)-4-NITROBENZENESULFONAMIDE(153312-38-0)
• EPA Substance Registry System: N-(4,6-DIMETHYL-2-PYRIMIDINYL)-4-NITROBENZENESULFONAMIDE(153312-38-0)

Safety Data

• Hazardous Substances Data: 153312-38-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H12N4O4S/c1-8-7-9(2)14-12(13-8)15-21(19,20)11-5-3-10(4-6-11)16(17)18/h3-7H,1-2H3,(H,13,14,15)

Upstream product

• 767-15-7 2-Amino-4,6-dimethylpyrimidine 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 42249-51-4 N-(4-nitrobenzenesulfonyl)guanidine 
• 123-54-6 acetylacetone 

Downstream Products

• 1267610-55-8 C₁₈H₂₇N₅O₂S 
• 1267610-50-3 2,4-dichloro-N-((4-(N-(2-(diethylamino)ethyl)-N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)carbamoyl)benzamide 
• 1267610-56-9 C₁₈H₂₅N₅O₄S 
• 35255-37-9 N-(4,6-dimethyl-pyrimidin-2-yl)-N-sulfanilyl-acetamide 
• 57-68-1 sulfadimesine 
• 106379-60-6 N-(4,6-dimethyl-pyrimidin-2-yl)-N-(4-nitro-benzenesulfonyl)-acetamide 

Relevant articles and documents

In vivo and in vitro anti-leishmanial activities of 4-nitro-N-pyrimidinand N-pyrazin-2-ylbenzenesulfonamides, and N2-(4-nitrophenyl)-N 1propylglycinamide

A series of compounds containing the nitrobenzene and sulfonamido moieties were synthesized and their leishmanicidal effect was assessed in vitro against Leishmania infantum promastigotes. Among the compounds evaluated, the p-nitrobenzenesulfonamides 4Aa