153334-55-5 Usage
Chemical compound
2-(3-hydroxy-2-pyridyl)-2-thiothiazoline is a chemical compound.
Thiothiazoline derivative
It is a derivative of thiothiazoline.
Thiazoline ring structure
It has a thiazoline ring structure.
Chelating metal ions
It has the ability to chelate metal ions.
Antioxidant properties
It has potential antioxidant properties.
Biological applications
It has potential biological applications due to its ability to chelate metal ions and its antioxidant properties.
Therapeutic chelating agent
It has been studied for its potential role in chelating metal ions for therapeutic purposes.
Antioxidant use
It has been studied for its potential use as an antioxidant in various applications.
Inhibiting biochemical processes
It has been investigated for its potential role in inhibiting some biochemical processes.
Pharmaceutical and medicinal chemistry use
It has potential use in pharmaceutical and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 153334-55-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,3,3 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 153334-55:
(8*1)+(7*5)+(6*3)+(5*3)+(4*3)+(3*4)+(2*5)+(1*5)=115
115 % 10 = 5
So 153334-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2OS2/c11-6-2-1-3-9-7(6)13-8-10-4-5-12-8/h1-3,11H,4-5H2
153334-55-5Relevant academic research and scientific papers
Synthesis and antithyroid activity of pyridine, pyrimidine and pyrazine derivatives of thiazole-2-thiol and 2-thiazoline-2-thiol
Lagorce,Comby,Rousseau,Buxeraud,Raby
, p. 1258 - 1260 (2007/10/02)
A series of compounds was synthesized by linking various derivatives of pyridine, pyrimidine or pyrazine to thiazole-2-thiol or to its partially hydrogenated derivative 2-thiazoline-2-thiol. The reactions of the compounds with molecular iodine and lactoperoxidase were examined in vitro. Their antithyroid activity was also examined in vivo in the rat. T4 and TSH levels were determined, and the thyroid gland was examined histologically. 2-(3- Hydroxy-2-pyridyl)-2-thiothiazoline had the highest antithyroid activity of the compounds tested (K(c) = 14931 · mol-1, IC50 0.65 x 10-4 M, activity of thyroid gland + + +).
