153335-34-3Relevant academic research and scientific papers
Room temperature palladium-catalyzed cross coupling of aryltrimethylammonium triflates with aryl grignard reagents
Reeves, Jonathan T.,Fandrick, Daniel R.,Tan, Zhulin,Song, Jinhua J.,Lee, Heewon,Yee, Nathan K.,Senanayake, Chris H.
supporting information; experimental part, p. 4388 - 4391 (2010/11/17)
Figure Presented. Aryltrimethylammonium triflates and tetrafluoroborates were found to be highly reactive electrophiles in the Pd-catalyzed cross coupling with aryl Grignard reagents. The coupling reactions proceed at ambient temperature with a nearly stoichiometric quantity of Grignard reagent, and diverse functionality is tolerated. Competition experiments established the reactivity of PhNMe3OTf relative to PhCl, PhBr, PhI, and PhOTf.
