1533409-66-3Relevant academic research and scientific papers
Asymmetric sonogashira coupling with a chiral palladium imidazoindole phosphine complex
Zhou, Haifeng,Uozumi, Yasuhiro
, p. 2550 - 2554 (2013)
The asymmetric Sonogashira coupling of 1-(2,6-di?-bromophenyl) naphthalene or 4,16-dibromo[2,2]paracyclophane with various terminal alkynes was carried out with a palladium complex of a homochiral imidazoindole phosphine, a derivative of a (3R,9aS)-2-aryl-[3-(2-dialkylphosphanyl)phenyl]tetrahydro-1H- imidazo[1,5a]indol-1-one, to give the corresponding axially chiral monoalkynylated biaryl products with up to 72% enantiomeric ?-excess. Georg Thieme Verlag Stuttgart · New York.
