153358-07-7Relevant academic research and scientific papers
Arene-ruthenium(II) complexes containing amino-phosphine ligands as catalysts for nitrile hydration reactions
Garcia-Alvarez, Rocio,Diez, Josefina,Crochet, Pascale,Cadierno, Victorio
scheme or table, p. 3955 - 3965 (2010/12/25)
Three different series of novel mononuclear arene-ruthenium(II) complexes containing amino-phosphine ligands, namely, [RuCl2{κ 1(P)-2-Ph2PC6H4CH 2NHR}(η6-arene)], [RuCl2{κ 1(P)-3-Ph2PC6H4CH 2NHR}(η6-arene)], and [RuCl2{κ 1(P)-4-Ph2PC6H4CH 2NHR}(η6-arene)] (arene = C6H6, p-cymene, 1,3,5-C6H3Me3, C6Me 6; R = iPr, tBu; all combinations), have been synthesized and fully characterized. These readily accessible species are efficient catalysts for the selective hydration of organonitriles into amides under challenging reaction conditions, i.e., pure aqueous medium in the absence of any cocatalyst, being much more active than their corresponding nonfunctionalized triphenylphosphine counterparts [RuCl2(PPh 3)(η6-arene)]. The results obtained in this study indicate that the (amino-phosphine)ruthenium(II) complexes operate through a "bifunctional catalysis" mechanism in which the ruthenium center acts as a Lewis acid, activating the nitrile molecule, and the P-donor ligand acts as a Brnsted base, the pendant amino group generating the real nucleophile of the hydration process, i.e., the OH- group.
POLYMERIZABLE DERIVATIVES OF TRIPHENYLPHOSPHINE. ACYLATION OF TRIARYLPHOSPHINES BEARING ALCOHOL OR AMINE SUBSTITUENTS WITH ACRYLOYLCHLORIDE AND METHACRYLOYLCHLORIDE
Nikitidis, Antonios,Andersson, Carlaxel
, p. 141 - 152 (2007/10/02)
Methods to prepare amino substituted triaryl-phosphines viz.N-methyl-2-(diphenylphosphino)benzylamine, N-t-butyl-2-(diphenylphosphino)benzylamine and α,N-dimethyl-4-(diphenylphosphino)benzylamine are presented.The acylation of amino and alcohol substituted triarylphosphines have been studied and the amides N-methacryloyl-N-methyl-4-(diphenylphosphino)benzylamine, N-methacryloyl-2-(diphenylphosphino)aniline, N-methacryloyl-N-methyl-4-(diphenylphosphino)benzylamine, N-methyl-N-propionyl-4-(diphenylphosphino)benzylamine, N-methyl-N-propionyl-2-(diphenylphosphino)benzylamine and N-acryloyl-N-methyl-4-(diphenylphosphino)benzylamine and the ester 2-(diphenylphosphino)benzyl methacrylate have been prepared. Key words: Phosphine; monomer; acylation; acryloylchloride; methacryloylchloride polymer-bound.
