153387-87-2

Basic information

• Product Name: (E)-4-Ethoxycarbonyl-5-methyl-3-(2-phenylethen-1-yl)isoxazole
• Synonyms: (E)-4-Ethoxycarbonyl-5-methyl-3-(2-phenylethen-1-yl)isoxazole
• CAS NO: 153387-87-2
• Molecular Weight: 257.289
• Mol File: 153387-87-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-4-Ethoxycarbonyl-5-methyl-3-(2-phenylethen-1-yl)isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-Ethoxycarbonyl-5-methyl-3-(2-phenylethen-1-yl)isoxazole(153387-87-2)
• EPA Substance Registry System: (E)-4-Ethoxycarbonyl-5-methyl-3-(2-phenylethen-1-yl)isoxazole(153387-87-2)

Safety Data

• Hazardous Substances Data: 153387-87-2(Hazardous Substances Data)

Upstream product

• 1449-46-3 benzyltriphenylphosphonium bromide 
• 180295-75-4 4-Ethoxycarbonyl-3-formyl-5-methylisoxazole 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 141-97-9 ethyl acetoacetate 
• 180295-72-1 4-Ethoxycarbonyl-3-(tetrahydropyran-2-yloxy)methyl-5-methylisoxazole 
• 180295-73-2 3-Diethoxymethyl-4-ethoxycarbonyl-5-methylisoxazole 
• 95104-47-5 ethyl 3-hydroxymethyl-5-methyl-4-isoxazolecarboxylate 
• 2723-42-4 ethyl 3-pyrrolidinobut-2-enoate 
• 100-52-7 benzaldehyde 

Relevant articles and documents

An alternative isoxazole route to α-alkoxycarbonyl-β-diketones

Cycloaddition of oxygen-functionalized nitrite oxides to the enamine from ethyl acetoacetate produces 4-ethoxycarbonyl-5-methylisoxazoles carrying a 3-tetrahydropyranyloxymethyl, 3-diethoxymethyl or 3-ethoxycarbonyl substituent; the 3-formylisoxazole is prepared from the former two and condensed in situ with phosphoranes to give 3-alkenylisoxazoles that are cleaved by hexacarbonylmolybdenum or hydrogenolysis to afford α-alkoxycarbonyl-β-diketones.