153391-35-6Relevant academic research and scientific papers
Chemical transformations on 6-aryl-3-cyano4-methylthio-pyran-2(h)-ones: Synthetic and structural studies on novel N-phenylpyrazoles and N-phenylpyrazolylcoumarins
Kumar, Ajay,Malhotra, Sanjay,Vats, Archana,Himanshu,Singh, Sanjay K.,Sharma, Sunil K.,Prasad, Ashok K.,Errington, William,Olsen, Carl E.,Jain, Subhash C.,Parmar, Virinder S.
, p. 360 - 367 (2007/10/03)
Seven 6-aryl-3-cyano-4-methylthiopyran-2(H)ones 1-7 have been prepared and used for the efficient synthesis of twelve 1,3-diaryl-5-cyanomethylpyrazoles 8-19, one 3-cyanomethyl-5-(3,4-methylenedioxyphenyl)pyrazole 22 and one 5-cyanomethyl-3-phenylisoxazole
Synthesis of E- and Z-Pyrazolylacrylonitriles and their evaluation as novel antioxidants
Parmar, Virinder S.,Kumar, Ajay,Prasad, Ashok K.,Singh, Sanjay K.,Kumar, Naresh,Mukherjee, Shubhasish,Raj, Hanumantharao G.,Goel, Sanjay,Errington, William,Puar, Mohindar S.
, p. 1425 - 1436 (2007/10/03)
A facile synthesis of (Z)- and (E)-2-(5-arylpyrazol-3-yl)-3-(pyrrol-2-yl)acrylonitriles and (Z)-2-(1,3-diarylpyrazol-5-yl)-3-(pyrrol-2-yl)acrylonitriles, and isomerisation of (Z)-2-(5-arylpyrazolyl)acrylonitriles to (E)-2-(5-arylpyrazolyl)acrylonitriles under basic conditions have been reported. (Z)-2-(1,3-Diarylpyrazolyl)acrylonitriles did not undergo isomerisation under the similar conditions. New compounds were identified on the basis of their spectral data (1H-, 13C-, 1H-1H COSY, NOESY, NOE, HMQC NMR, IR, UV and EI mass). The structures of one acrylonitrile and five of their precursor 6-arylpyran-2-ones and cyanomethylpyrazoles were confirmed by X-ray crystallographic studies. Effects of pyrazolylacrylonitriles and their precursors on rat liver-microsomal lipid peroxidation were evaluated in vitro with a view to establish structure-activity relationship and to identify a lead compound. Copyright (C) 1999 Elsevier Science Ltd.
Ring transformation reaction: Part II - Reaction specificity of hydrazines towards 6-aryl-4-(methylthio)-2-oxo-2H-pyran-3-carbonitriles and corresponding 3-ethyl carboxylate
Ram, Vishnu Ji,Haque, Navedul,Singh, Sanjay Kumar,Hussaini, Falak Anwer,Shoeb, Aboo
, p. 924 - 928 (2007/10/02)
Reaction specificity of hydrazine hydrate, cyclohexyl- and phenyl-hydrazines towards 6- or 5,6-disubstituted-4-(methylthio)-2-oxo-2H-pyran-3-carbonitriles and the corresponding 3-ethyl carboxylate (1,8) has been studied.
