1534-28-7

Basic information

• Product Name: 2-Undecanone, 3-methyl-
• CAS NO: 1534-28-7
• Molecular Formula: C12H24O
• Molecular Weight: 184.322
• Mol File: 1534-28-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Undecanone, 3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Undecanone, 3-methyl-(1534-28-7)
• EPA Substance Registry System: 2-Undecanone, 3-methyl-(1534-28-7)

Safety Data

• Hazardous Substances Data: 1534-28-7(Hazardous Substances Data)

Upstream product

• 1046464-00-9 2-chloro-3-methyl-2-(toluene-4-sulfinyl)undecan-2-ol 
• 111-83-1 1-bromo-octane 
• 6125-75-3 N-cyclohexylbutylidene-2-imine 
• 111-66-0 oct-1-ene 
• 78-93-3 butanone 

Relevant articles and documents

One-carbon homologation of unsymmetrical ketones through magnesium β-oxido carbenoid rearrangement and trapping the enolate intermediates with electrophiles

A procedure for one-carbon homologation of unsymmetrical ketones, including one-carbon ring-expansion of 2-substituted cyclohexanones, through magnesium β-oxido carbenoid rearrangement as the key reaction is described. Addition of the α-sulfinyl carbanion of 1-chloroethyl p-tolyl sulfoxide to an unsymmetrical ketone gave two diastereomers as adducts in good yields. The adducts were treated with a base to give alkoxides, which were treated with a Grignard reagent to give magnesium β-oxido carbenoids. The β-oxido carbenoid rearrangement then took place to afford one-carbon homologated ketones having a methyl group at the α-position. Remarkable specificity or selectivity was observed in the rearrangement. The magnesium enolate intermediates of this reaction were found to be able to get trapped with several electrophiles to give one-carbon homologated α,α-disubstituted ketones. Origin of the specificity and selectivity is also discussed.

HIGHLY DISPERSED POTASSIUM ON ALUMINA AS A METALATING AGENT. ALKYLATION OF ENOLIZABLE COMPOUNDS

Highly dispersed potassium on alumina (K/Al2O3) acts as a metalating agent towards enolizable compounds and the intermediate organopotassium derivatives can be alkylated with primary alkyl bromides.The reaction conditions are dependent on the substrate.In particular, tetrahydrofuran is the solvent of choice for the metalation of nitriles and aldehyde N,N-dimethylhydrazones at -60 deg C and of N-cyclohexyl ketimines at room temperature, whereas hexane must be used for ketones.