153440-80-3

Basic information

• Product Name: ((R)-1-Benzyl-aziridin-2-yl)-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone
• CAS NO: 153440-80-3
• Molecular Weight: 374.504
• Mol File: 153440-80-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((R)-1-Benzyl-aziridin-2-yl)-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: ((R)-1-Benzyl-aziridin-2-yl)-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone(153440-80-3)
• EPA Substance Registry System: ((R)-1-Benzyl-aziridin-2-yl)-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone(153440-80-3)

Safety Data

• Hazardous Substances Data: 153440-80-3(Hazardous Substances Data)

Upstream product

• 119944-89-7 (2S)-N-(acryloyl)bornane-10,2-sultam 
• 635678-42-1 (1R,2S,4S)-N-(2,3-dibromopropionyl)-bornane-2,10-sultam 
• 100-46-9 benzylamine 

Downstream Products

• 127556-03-0 (2R)-N-{N-[bis(methylthio)methylidene]glycyl}bornane-10,2-sultam 
• 108448-77-7 (+)-camphorsultam 
• 332041-84-6 [3aR-[(3aR*,4R*,6aS*),3aα,6α,7aβ]]-3H-3a,6-methano-2,1-benzisothiazole, hexahydro-8,8-dimethyl-4-[[tetrahydro-1,3-dioxolo-5-(phenylmethyl)-2-oxo-[4,5-c]-pyrrol-4-yl]carbonyl]-2,2-dioxide 
• 332041-85-7 [3aR-[(3aS*,4S*,6aR*),3aα,6α,7aβ]]-3H-3a,6-methano-2,1-benzisothiazole, hexahydro-8,8-dimethyl-4-[[tetrahydro-1,3-dioxolo-5-(phenylmethyl)-2-oxo-[4,5-c]-pyrrol-4-yl]carbonyl]-2,2-dioxide 

Relevant articles and documents

Stereocontrolled 1,3-dipolar cycloadditions using Oppolzer's camphor sultam as the chiral auxiliary for carbonyl stabilized azomethine ylides

Two complementary approaches to substituted pyrrolidines via stereocontrolled 1,3-dipolar cycloaddition reactions of chiral azomethine ylides are described. In one approach, chiral azomethine ylides were generated by thermolysis of aziridine carboxylate sultams and trapped with a variety of dipolarophiles to give good yields of the corresponding cycloadducts. In the second approach, chiral azomethine ylides were generated from glycyl sultams by 'imine tautomerization' and trapped with dipolarophiles to give good yields of the corresponding cycloadducts.