119944-89-7

Basic information

• Product Name: N-Acryloyl-(2S)-bornane-10,2-sultam
• Synonyms: N-Acryloyl-(2S)-bornane-10,2-sultam
• CAS NO: 119944-89-7
• Molecular Weight: 269.35986
• Mol File: 119944-89-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-Acryloyl-(2S)-bornane-10,2-sultam(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acryloyl-(2S)-bornane-10,2-sultam(119944-89-7)
• EPA Substance Registry System: N-Acryloyl-(2S)-bornane-10,2-sultam(119944-89-7)

Safety Data

• Hazardous Substances Data: 119944-89-7(Hazardous Substances Data)

Usage

General Description

N-Acryloyl-(2S)-bornane-10,2-sultam is a chemical compound used in the production of pharmaceuticals and as a building block for synthesizing other compounds. It is a derivative of the natural product camphor and contains a sultam moiety, which confers unique chemical and biological properties. N-Acryloyl-(2S)-bornane-10,2-sultam is particularly valued for its ability to act as a chiral auxiliary in asymmetric transformations, enabling the efficient and selective synthesis of complex molecules. N-Acryloyl-(2S)-bornane-10,2-sultam has applications in drug development, materials science, and other fields where precise control over molecular structure is important. Additionally, its unique chemical properties make it a valuable tool for studying reaction mechanisms and developing new synthetic methods.

Upstream product

• 108448-77-7 (+)-camphorsultam 
• 814-68-6 acryloyl chloride 
• 124170-22-5 (+)-(1R,5S)-N-(trimethylsilyl)bornane-2,10-sultam 
• 625-36-5 2-chloropropionyl chloride 

Downstream Products

• 1161025-66-6 C₂₄H₃₂N₂O₆S 
• 139527-61-0 (2-{(R)-1-[(1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-8-methyl-2,4-dioxo-3,8-diaza-bicyclo[3.2.1]oct-3-yl]-2-methoxymethoxy-ethyl}-3-methoxy-benzyl)-triphenyl-phosphonium; bromide 
• 139527-60-9 (1R,5S,6R)-3-[(R)-1-(2-Bromomethyl-6-methoxy-phenyl)-2-methoxymethoxy-ethyl]-6-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 139527-59-6 (1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-3-[(R)-2-methoxymethoxy-1-(2-methoxy-6-methyl-phenyl)-ethyl]-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 332041-84-6 [3aR-[(3aR*,4R*,6aS*),3aα,6α,7aβ]]-3H-3a,6-methano-2,1-benzisothiazole, hexahydro-8,8-dimethyl-4-[[tetrahydro-1,3-dioxolo-5-(phenylmethyl)-2-oxo-[4,5-c]-pyrrol-4-yl]carbonyl]-2,2-dioxide 
• 153440-81-4 ((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-[(R)-1-(4-methoxy-phenyl)-aziridin-2-yl]-methanone 
• 153440-80-3 ((R)-1-Benzyl-aziridin-2-yl)-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone 

Relevant articles and documents

TETRAPEPTIDE ANALOGS

Compounds, compositions and methods for treatment of hyperproliferative diseases, such as cancer are provided.

A Practical and Efficient Large-Scale Preparation of (4R,58)-N-Propenoyl-1,5-dimethyl-4-phenylimidazolidin-2-one. A Simple Procedure for the Preparation of N-Acylimidazolidin-2-ones and N-Acylbornane 2,10-Sultams

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Asymmetric silyl nitronate cycloadditions with bornane-10,2-sultam derivatives

Asymmetric silyl nitronate cycloadditions with N-acryloyl (2R)-bornane-10,2-sultam, N-acryloyl (2S)-bornane-10,2-sultam, and N-methacryloyl (2R)-bornane-10,2-sultam have been studied. The asymmetric silyl nitronate cycloaddition/elimination methodology pr