119944-89-7

Usage

Uses

Used in Pharmaceutical Production:
N-Acryloyl-(2S)-bornane-10,2-sultam is used as a chiral auxiliary for the production of pharmaceuticals, enabling the efficient and selective synthesis of complex molecules with specific biological activities.
Used in Asymmetric Transformations:
In the field of organic chemistry, N-Acryloyl-(2S)-bornane-10,2-sultam is used as a chiral auxiliary for asymmetric transformations, allowing chemists to control the stereochemistry of reactions and produce enantiomerically pure compounds.
Used in Drug Development:
N-Acryloyl-(2S)-bornane-10,2-sultam is used as a building block in drug development, providing a foundation for the creation of new pharmaceuticals with potential therapeutic applications.
Used in Materials Science:
In materials science, N-Acryloyl-(2S)-bornane-10,2-sultam is used for the synthesis of novel materials with specific properties, contributing to advances in areas such as polymer science and nanotechnology.
Used in Research and Development:
N-Acryloyl-(2S)-bornane-10,2-sultam is used as a research tool for studying reaction mechanisms and developing new synthetic methods, furthering the understanding of chemical processes and innovation in synthetic techniques.

Upstream product

• 108448-77-7 (+)-camphorsultam 
• 814-68-6 acryloyl chloride 
• 124170-22-5 (+)-(1R,5S)-N-(trimethylsilyl)bornane-2,10-sultam 
• 625-36-5 2-chloropropionyl chloride 

Downstream Products

• 5709-98-8 (R)-cyclohex-3-enecarboxylic acid 
• 5708-19-0 (1S)-3-cyclohexenecarboxylic acid 
• 94594-79-3 (+)-N-<(R)-cyclohex-3-enylcarbonyl>bornane-10,2-sultam 
• 94594-79-3 (S)-Cyclohex-3-enyl-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone 
• 128869-18-1 4-((1R)-2-methylenecyclopentyl-1-oxomethyl)-(7R)-10,10-dimethyl-5-thia-4-azatricyclo<5.2.1.0^3,7>decane-5,5-dioxide 
• 128947-24-0 4-((1S)-2-methylenecyclopentyl-1-oxomethyl)-(7R)-10,10-dimethyl-5-thia-4-azatricyclo<5.2.1.0^3,7>decane-5,5-dioxide 
• 128947-25-1 4-((2S)-2-cyclohexylmethyl-1-oxopent-4-enyl)-(7R)-10,10-dimethyl-5-thia-4-azatricyclo<5.2.1.0>decane-5,5-dioxide 
• 128869-14-7 4-((2R)-2-cyclohexylmethyl-1-oxopent-4-enyl)-(7R)-10,10-dimethyl-5-thia-4-azatricyclo<5.2.1.0>decane-5,5-dioxide 
• 139527-59-6 (1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-3-[(R)-2-methoxymethoxy-1-(2-methoxy-6-methyl-phenyl)-ethyl]-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 139527-60-9 (1R,5S,6R)-3-[(R)-1-(2-Bromomethyl-6-methoxy-phenyl)-2-methoxymethoxy-ethyl]-6-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-8-methyl-3,8-diaza-bicyclo[3.2.1]octane-2,4-dione 
• 139527-61-0 (2-{(R)-1-[(1R,5S,6R)-6-((1R,5S,7S)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-8-methyl-2,4-dioxo-3,8-diaza-bicyclo[3.2.1]oct-3-yl]-2-methoxymethoxy-ethyl}-3-methoxy-benzyl)-triphenyl-phosphonium; bromide 
• 1161025-66-6 C₂₄H₃₂N₂O₆S 

Relevant academic research and scientific papers

TETRAPEPTIDE ANALOGS

Compounds, compositions and methods for treatment of hyperproliferative diseases, such as cancer are provided.

Investigation of Lewis Acid-Catalyzed Asymmetric Aza-Diels-Alder Reactions of 2H-Azirines

Asymmetric Diels-Alder reactions with 2H-azirines as dienophiles have been studied. Diastereoselective reactions with an enantiopure azirine 1b, bearing a chiral auxiliary, gave substituted bi- and tricyclic tetrahydropyridines in high yield and stereoselectivity, under the influence of a Lewis acid. The novel enantioselective [4+2] cycloaddition reaction of 3-benzyl-2H-azirine carboxylate with cyclopentadiene was investigated with various chiral Lewis acid complexes and provided the corresponding tetrahydropyridines in moderate to low yield and enantioselectivity.

A practical method for N-acylation of bornane-2,10-sultam and 2-oxazolidinones

The N-trimethylsilyl derivatives of (+)-bornane-2,10-sultam (10,10-dimethyl-5-thia-4-azatricyclo[5.2.1.03,7]decane 5,5-dioxide) and (R)-4-benzyl-2-oxazolidinone and 4-methyl-5-phenyl-2-oxazolidinone react with acid chlorides in refluxing benzen

Asymmetric silyl nitronate cycloadditions with bornane-10,2-sultam derivatives

Asymmetric silyl nitronate cycloadditions with N-acryloyl (2R)-bornane-10,2-sultam, N-acryloyl (2S)-bornane-10,2-sultam, and N-methacryloyl (2R)-bornane-10,2-sultam have been studied. The asymmetric silyl nitronate cycloaddition/elimination methodology pr

On the Scope of Asymmetric Nitrile Oxide Cycloadditions with Oppolzer's Chiral Sultam. Total Syntheses of (+)-Hepialone, (-)-(1R,3R,5S)-1,3-Dimethyl-2,9-dioxabicyclooctane

Cycloadditions of nitrile oxides with acryloyl derivatives of Oppolzer's chiral sultam produce stereoisomeric Δ2-isoxazolines in ratios of about 90/10 at 25 deg C.The major diastereomers can be isolated in pure form in 70-88percent yield.Synthe