153446-74-3Relevant articles and documents
One-pot synthesis of 3-haloflavones from flavones using Oxone and potassium halide as a halogenation reagent
Peng, Tao,Wang, Gang,Zhang, Shouguo,Sun, Yunbo,Liu, Shuchen,Wang, Lin
, (2019/12/27)
A two-step, one-pot method has been developed for the synthesis of 3-haloflavones from the corresponding flavones. The method uses Oxone and potassium halide to produce the active molecular halogen in situ. The solvent (methanol) then participates in the reaction to afford the 2-methoxy-3-haloflavanone derivative. After adding sodium hydroxide, the corresponding 3-haloflavone product is obtained in good to excellent yields. This method provides a convenient synthesis of 3-chloro, 3-bromo and 3-iodo flavones from the same flavone starting material.
Synthesis of 3-iodo derivatives of flavones, thioflavones and thiochromones
Zhang,Li
, p. 565 - 567 (2007/10/02)
The title compounds, 2-aryl-3-iodo-4H-1-benzopyrans and 2-alkyl or 2-aryl-3-iodo-4H-1-benzothiopyrans, were prepared by reaction of the corresponding heterocyclic derivatives with the iodine-cerium(IV) ammonium nitrate system under mild conditions. The scope and proposed mechanism of the reaction were also demonstrated.