153473-49-5

Basic information

• Product Name: 2-[4-(1H-indol-2-ylcarbonyl)-1-piperazinyl]phenyl methyl ether
• Synonyms: 2-[4-(1H-indol-2-ylcarbonyl)-1-piperazinyl]phenyl methyl ether
• CAS NO: 153473-49-5
• Molecular Formula: C20H21N3O2
• Molecular Weight: 335.39964
• Mol File: 153473-49-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[4-(1H-indol-2-ylcarbonyl)-1-piperazinyl]phenyl methyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(1H-indol-2-ylcarbonyl)-1-piperazinyl]phenyl methyl ether(153473-49-5)
• EPA Substance Registry System: 2-[4-(1H-indol-2-ylcarbonyl)-1-piperazinyl]phenyl methyl ether(153473-49-5)

Safety Data

• Hazardous Substances Data: 153473-49-5(Hazardous Substances Data)

Upstream product

• 1477-50-5 Indole-2-carboxylic acid 
• 35386-24-4 1-(2-Methoxyphenyl)piperazine 
• 58881-45-1 Indole-2-carbonyl chloride 
• 3770-50-1 2-carbethoxyindole 

Relevant articles and documents

Indoles and pyridazinoindoles as nonnucleoside analog inhibitors of HIV-1 reverse transcriptase

The synthesis and the study of the activity of new indol-2-carboxamides and pyridazinoindoles as inhibitors of HIV-1 reverse transcriptase (RT) are presented.The activity of the compounds synthesized as inhibitors of different types of HIV-1 RT (wild type enzyme and mutant forms P236L, Y181C and P236L/Y181C) was evaluated.The activity of the most active compounds was investigated in the syncytia reduction in vitro assay, in HIV-1IIIB-infected HT4lacZ-1 cells.Their potential cytotoxicity was determined in parallel.Two lead compounds,N-piperazin>-5,6-methylenedioxy indol-2-carboxamide 7q and N-piperazin>-5,6-methylenedioxyindol-2-carboxamide 7s have been identified. - Keywords: indole; nonnucleoside RT inhibitor; syncytia assay; HIV-1IIIBHT4lacZ-1 cells