1535-57-5 Usage
Uses
Used in Pharmaceutical Industry:
L-N-Trifluoroacetylglutamic anhydride is used as a reagent in organic synthesis for the production of pharmaceuticals. Its ability to acylate and alkylate amines and alcohols makes it a valuable tool for the modification of biomolecules, leading to the development of new drug candidates with improved properties.
Used in Agrochemical Industry:
In the agrochemical industry, L-N-Trifluoroacetylglutamic anhydride is utilized as a reagent in the synthesis of agrochemicals. Its reactivity allows for the creation of novel chemical structures that can be used in the development of new pesticides, herbicides, and other agricultural chemicals.
It is important to handle L-N-Trifluoroacetylglutamic anhydride with caution due to its high volatility and potential to cause irritation to the skin, eyes, and respiratory system if not properly controlled.
Check Digit Verification of cas no
The CAS Registry Mumber 1535-57-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,3 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1535-57:
(6*1)+(5*5)+(4*3)+(3*5)+(2*5)+(1*7)=75
75 % 10 = 5
So 1535-57-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3NO4/c8-7(9,10)6(14)11-3-1-2-4(12)15-5(3)13/h3H,1-2H2,(H,11,14)/t3-/m0/s1
1535-57-5Relevant academic research and scientific papers
PROCESSES FOR PREPARING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES
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Page/Page column 15; 17; 20, (2020/10/21)
The disclosure provides processes for preparing α-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, as well as intermediates for use in said processes.
The Synthesis of the High-Potency Sweetener, NC-00637. Part 3: The Glutamyl Moiety and Coupling Reactions
Ager, David J.,Babler, Scott,Erickson, Robert A.,Froen, Diane E.,Kittleson, Jeannine,Pantaleone, David P.,Prakash, Indra,Zhi, Ben
, p. 72 - 85 (2013/09/04)
The synthesis of the high-potency sweetener, NC-00637 (1), required selective preparation of the γ-protected glutamic acid. Coupling of the three components could be performed in any order, but the final route involved N-acylation of the protected L-glutamic acid with the acid chloride derived from (S)-2-methylhexanoic acid. Activation of the α-carboxyl group allowed condensation with 5-amino-2-cyanopyridine (4). Saponification of the γ-ester 19 then provided the sweetener 1.
A TOTAL SYNTHESIS OF LEUKOTRIENE F4 (LTF4)
Ellis, Frank,Mills, Lester S.,North, Peter C.
, p. 3735 - 3736 (2007/10/02)
The synthesis of LTF4 via the reaction of (+/-)-leukotriene A4(LTA4), methyl ester 1 with the protected glutamylcysteine 2 is reported.
