153500-78-8Relevant articles and documents
Indole derivative and medical application thereof
-
Paragraph 0121; 0124; 0126; 0127, (2020/12/15)
The invention discloses an indole compound with FABP4/5 inhibitory activity and a preparation method and medical application of the indole compound. The indole compound is a compound of which the structural formula is shown as a formula I, and pharmaceutically acceptable salt or ester or solvate of the compound. The compound shown in the formula I is a novel FABP4/5 inhibitor and can be used for preparing medicines for preventing or treating FABP4/5 related diseases.
3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF
-
, (2017/10/06)
The present invention provides compounds, compositions thereof, and methods of using the same.
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: Role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity
La Regina, Giuseppe,Coluccia, Antonio,Piscitelli, Francesco,Bergamini, Alberto,Sinistra, Anna,Cavazza, Antonella,Maga, Giovanni,Samuele, Alberta,Zanoli, Samantha,Novellino, Ettore,Artico, Marino,Silvestri, Romano
, p. 5034 - 5038 (2008/03/14)
Indolyl aryl sulfones bearing the 4,5-difluoro (10) or 5-chloro-4-fluoro (16) substitution pattern at the indole ring were potent inhibitors of HIV-1 WT and the NNRTI-resistant strains Y181C and K103N-Y181C. These compounds were highly effective against t
