1535207-52-3

Basic information

• Product Name: ([1,1′-biphenyl]-4-yl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)trimethylsilane
• Synonyms: ([1,1′-biphenyl]-4-yl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)trimethylsilane
• CAS NO: 1535207-52-3
• Molecular Weight: 366.383
• Mol File: 1535207-52-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ([1,1′-biphenyl]-4-yl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)trimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: ([1,1′-biphenyl]-4-yl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)trimethylsilane(1535207-52-3)
• EPA Substance Registry System: ([1,1′-biphenyl]-4-yl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)trimethylsilane(1535207-52-3)

Safety Data

• Hazardous Substances Data: 1535207-52-3(Hazardous Substances Data)

Upstream product

• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 5122-94-1 4-biphenylboronic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 1535207-45-4 (bis(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)methyl)trimethylsilane 
• 78782-17-9 4,4,5,5-tetramethyl-2-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-1,3,2-dioxaborolane 

Relevant articles and documents

Metal-free synthesis of gem -silylboronate esters and their Pd(0)-catalyzed cross-coupling with aryliodides

A transition-metal-free method for the synthesis of gem-silylboronate esters with arylboronic acids and trimethylsilyldiazomethane (TMSCHN2) has been developed. This transformation is a straightforward homologation of arylboronic acids and features wide substrate scope and good functional-group tolerance. The gem-silylboronate esters undergo efficient Suzuki-Miyaura cross-coupling with aryliodides and the silyl group of the product can be further functionalized. Tertiary carbon centers with different substituents can be constructed successfully by selective and sequential functionalization.