1535207-53-4Relevant academic research and scientific papers
Metal-free synthesis of gem -silylboronate esters and their Pd(0)-catalyzed cross-coupling with aryliodides
Wu, Chaoqiang,Bao, Zhicheng,Xu, Xing,Wang, Jianbo
, p. 5714 - 5724 (2019/06/18)
A transition-metal-free method for the synthesis of gem-silylboronate esters with arylboronic acids and trimethylsilyldiazomethane (TMSCHN2) has been developed. This transformation is a straightforward homologation of arylboronic acids and features wide substrate scope and good functional-group tolerance. The gem-silylboronate esters undergo efficient Suzuki-Miyaura cross-coupling with aryliodides and the silyl group of the product can be further functionalized. Tertiary carbon centers with different substituents can be constructed successfully by selective and sequential functionalization.
Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids
Bomio, Claudio,Kabeshov, Mikhail A.,Lit, Arthur R.,Lau, Shing-Hing,Ehlert, Janna,Battilocchio, Claudio,Ley, Steven V.
, p. 6071 - 6075 (2017/08/29)
By means of computational and experimental mechanistic studies the fundamental role of boroxines in the reaction between diazo compounds and boronic acids was elucidated. Consequently, a selective metal-free carbon-carbon homologation of aryl and vinyl boroxines using TMSCHN2, giving access to TMS-pinacol boronic ester products, was developed.
Silver(I) oxide-promoted chemoselective cross-coupling reaction of (Diborylmethyl)trimethylsilane
Endo, Kohei,Kurosawa, Fumiya,Ukaji, Yutaka
supporting information, p. 1363 - 1365 (2013/11/19)
The present paper describes a synergistic effect in the Pdcatalyzed SuzukiMiyaura cross-coupling reaction. The chemoselective cross-coupling reaction of (diborylmethyl)trimethylsilane and aryl halides proceeded at room temperature when a silver salt and K
