153545-11-0

Upstream product

• 153463-27-5 (R)-3-[(3R,4S)-1-(4-Methoxy-phenyl)-2-oxo-4-phenyl-azetidin-3-yl]-4-phenyl-oxazolidin-2-one 
• 40339-42-2 4-methoxy-N-[(1Z)-phenylmethylene]aniline 
• 956474-74-1 C₂₃H₂₅NO₆ 
• 956474-86-5 C₂₀H₂₁NO₆ 

Downstream Products

• 146924-94-9 (3R,4S)-(+)-3-hydroxy-1-(4-methoxyphenyl)-4-phenyl-2-azetidinone 
• 1399842-86-4 C₂₅H₂₁NO₃ 
• 1399843-04-9 C₂₅H₁₉NO₂ 
• 146924-90-5 (+)-cis-(3R,4S)-3-acetoxy-1-(4-methoxyphenyl)-4-phenyl-2-azetidinone 
• 144790-01-2 (3R-cis)-3-acetyloxy-4-phenyl-2-azetidinone 

Relevant academic research and scientific papers

An efficient synthesis of azetidine-2,3-diones from L-(+)-diethyl tartrate

A convenient route to enantiopure azetidine-2,3-diones is described. The chiral ketene generated from commercially available L-(+)-diethyl tartrate on Staudinger cycloaddition with different imines gave spiro-β-lactams in good yields. These spiro-β-lactam

Asymmetric synthesis of α-keto β-lactams via [2+2] cycloaddition reaction: A concise approach to optically active α-hydroxy β-lactams and β-alkyl(aryl)isoserines

The cycloaddition reaction of the Evans-Sjogren ketenes to imines, followed by α-hydroxylation of the resulting cycloadducts provides an efficient general asymmetric synthesis of α-keto β-lactams and derivatives.