153546-27-1

Basic information

• Product Name: (2R)-2-cyclohexyloxirane
• Synonyms: (2R)-2-Cyclohexyloxirane; oxirane, 2-cyclohexyl-, (2R)-
• CAS NO: 153546-27-1
• Molecular Formula: C₈H₁₄O
• Molecular Weight: 126.1962
• Mol File: 153546-27-1.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 167.5°C at 760 mmHg
• Flash Point: 41.5°C
• Density: 1.014g/cm³
• Vapor Pressure: 2.24mmHg at 25°C
• Refractive Index: 1.499
• CAS DataBase Reference: (2R)-2-cyclohexyloxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-cyclohexyloxirane(153546-27-1)
• EPA Substance Registry System: (2R)-2-cyclohexyloxirane(153546-27-1)

Safety Data

• Hazardous Substances Data: 153546-27-1(Hazardous Substances Data)

Upstream product

• 139040-39-4 1,1,1-trichloro(cyclohexyl)ethan-2-one 
• 695-12-5 vinylcyclohexane 
• 3483-39-4 Cyclohexyloxirane 
• 4248-19-5 tert-butyl carbazate 
• 61414-09-3 1-cyclohexylethane-1,2-diol 
• 5664-21-1 cyclohexylacetaldehyde 
• 143-33-9 sodium cyanide 
• 51-79-6 urethane 
• 111324-03-9 1-tert-butyl-2,2,4,4,4-pentakis(dimethylamino)-2Λ⁵,4Λ⁵-catenadi(phosphazene) 
• 2043-61-0 cyclohexanecarbaldehyde 
• 90202-27-0 (+/-)-2-chloro-1-cyclohexylethanol 

Downstream Products

• 69036-26-6 (S)-1-cyclohexylbut-3-en-1-ol 
• 1305340-50-4 C₁₃H₂₀O₂ 
• 1305340-24-2 (S)-6-cyclohexyl-5,6-dihydro-2H-pyran-2-one 
• 1305340-52-6 C₂₅H₃₂O₆ 
• 1305340-53-7 C₂₆H₃₄O₆ 
• 1305340-30-0 C₂₃H₂₈O₅ 

Relevant articles and documents

Direct and Enantioselective Organocatalytic α-Chlorination of Aldehydes

The first direct enantioselective catalytic α-chlorination of aldehydes has been accomplished. The use of enamine catalysis has provided a new organocatalytic strategy for the enantioselective chlorination of aldehydes to generate α-chloro aldehydes, an i

Azidolysis of epoxides catalysed by the halohydrin dehalogenase from Arthrobacter sp. AD2 and a mutant with enhanced enantioselectivity: an (S)-selective HHDH

Halohydrin dehalogenase from Arthrobacter sp. AD2 catalysed azidolysis of epoxides with high regioselectivity and low to moderate (S)-enantioselectivity (E?=?1–16). Mutation of the asparagine 178 to alanine (N178A) showed increased enantioselectivity towards styrene oxide derivatives and glycidyl ethers. Conversion of aromatic epoxides was catalysed by HheA-N178A with complete enantioselectivity, however the regioselectivity was reduced. As a result of the enzyme-catalysed reaction, enantiomerically pure (S)-β-azido alcohols and (R)-α-azido alcohols (ee???99%) were obtained.

Photocatalytic Asymmetric Epoxidation of Terminal Olefins Using Water as an Oxygen Source in the Presence of a Mononuclear Non-Heme Chiral Manganese Complex

Photocatalytic enantioselective epoxidation of terminal olefins using a mononuclear non-heme chiral manganese catalyst, [(R,R-BQCN)MnII]2+, and water as an oxygen source yields epoxides with relatively high enantioselectivities (e.g., up to 60% enantiomeric excess). A synthetic mononuclear non-heme chiral Mn(IV)-oxo complex, [(R,R-BQCN)MnIV(O)]2+, affords similar enantioselectivities in the epoxidation of terminal olefins under stoichiometric reaction conditions. Mechanistic details of each individual step of the photoinduced catalysis, including formation of the Mn(IV)-oxo intermediate, are discussed on the basis of combined results of laser flash photolysis and other spectroscopic methods.