153567-07-8Relevant articles and documents
Synthesis of Naltrexone-Derived δ-Opioid Antagonists. Role of Conformation of the δ Address Moiety
Portoghese, P. S.,Sultana, M.,Moe, S. T.,Takemori, A. E.
, p. 579 - 585 (1994)
Naltrindole (1) (NTI) is a highly potent and selective δ-opioid receptor antagonist.In an effort to understand the origin of the high potency, affinity, and selectivity of NTI, we have examined the conformational role of its indolic benzene moiety through