Journal of Medicinal Chemistry p. 579 - 585 (1994)
Update date:2022-08-03
Topics:
Portoghese, P. S.
Sultana, M.
Moe, S. T.
Takemori, A. E.
Naltrindole (1) (NTI) is a highly potent and selective δ-opioid receptor antagonist.In an effort to understand the origin of the high potency, affinity, and selectivity of NTI, we have examined the conformational role of its indolic benzene moiety through
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