153647-48-4

Upstream product

• 60789-87-9 1,2,3,4-tetrahydrophthalazine hydrochloride 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 

Downstream Products

• 159720-62-4 {2-[3-(2-Amino-acetyl)-3,4-dihydro-1H-phthalazin-2-yl]-2-oxo-ethyl}-carbamic acid benzyl ester 
• 159720-63-5 {2-[3-((S)-2-Amino-propionyl)-3,4-dihydro-1H-phthalazin-2-yl]-2-oxo-ethyl}-carbamic acid benzyl ester 
• 159720-64-6 {2-[3-((S)-2-Amino-3-methyl-butyryl)-3,4-dihydro-1H-phthalazin-2-yl]-2-oxo-ethyl}-carbamic acid benzyl ester 
• 153647-52-0 {(S)-2-[3-(2-Benzyloxycarbonylamino-acetyl)-3,4-dihydro-1H-phthalazin-2-yl]-1-methyl-2-oxo-ethyl}-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 153647-55-3 {(S)-1-[3-(2-Benzyloxycarbonylamino-acetyl)-3,4-dihydro-1H-phthalazine-2-carbonyl]-2-methyl-propyl}-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 153647-51-9 {2-[3-(2-Benzyloxycarbonylamino-acetyl)-3,4-dihydro-1H-phthalazin-2-yl]-2-oxo-ethyl}-carbamic acid 9H-fluoren-9-ylmethyl ester 

Relevant academic research and scientific papers

Peptide Bond Formation via an Intramolecular Rearrangement

Intramolecular peptide synthesis could be achieved using tetrahydrophthalazine (1) as template.Peptide bond formation proceeded via the N-acyl-N'-α-aminoacylhydrazine-rearrangement.The feasibility of the approach is illustrated by the synthesis of the pro