
Tetrahedron Letters p. 7123 - 7126 (1993)
Update date:2022-08-04
Topics:
Wijkmans, Jac C. H. M.
Boom, Jacques H. van
Bloemhoff, Wim
Intramolecular peptide synthesis could be achieved using tetrahydrophthalazine (1) as template.Peptide bond formation proceeded via the N-acyl-N'-α-aminoacylhydrazine-rearrangement.The feasibility of the approach is illustrated by the synthesis of the pro
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Doi:10.1021/acs.jmedchem.6b01489
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