153687-35-5

Usage

Uses

Used in Organic Synthesis:
1-(4-Methoxy-benzyl)-1H-pyrazole-4-carbaldehyde is utilized as a building block in organic synthesis for the creation of more complex molecules. Its versatile structure allows for the development of a wide range of chemical entities, contributing to the advancement of chemical research and innovation.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-Methoxy-benzyl)-1H-pyrazole-4-carbaldehyde is employed as a potential precursor for the synthesis of pharmaceutical compounds. Its structural features suggest that it could be instrumental in the design and synthesis of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Pharmaceutical Industry:
1-(4-Methoxy-benzyl)-1H-pyrazole-4-carbaldehyde is used as a key intermediate in the pharmaceutical industry for the development of novel therapeutic agents. Its unique chemical properties and potential biological activity make it a valuable component in the formulation of new drugs, potentially leading to breakthroughs in the treatment of various diseases and conditions.
Used in Research and Development:
1-(4-Methoxy-benzyl)-1H-pyrazole-4-carbaldehyde is also used in research and development settings to explore its potential applications and properties. Scientists and researchers leverage 1-(4-Methoxy-benzyl)-1H-pyrazole-4-carbaldehyde to investigate its reactivity, stability, and interactions with other molecules, thereby enhancing the understanding of its role in chemical and biological systems.

Upstream product

• 145162-51-2 1-(p-methoxyphenyl)methyl-pyrazole 
• 68-12-2 N,N-dimethyl-formamide 
• 824-94-2 p-methoxybenzyl chloride 
• 35344-95-7 1H-pyrazole-4-carbaldehyde 

Downstream Products

• 35344-95-7 1H-pyrazole-4-carbaldehyde 

Relevant academic research and scientific papers

SMYD INHIBITORS

The present disclosure provides carboxamides and sulfonamides having Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein A, Y, B, X, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.

HETEROARYLAMINO-PHENYLKETONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS

The present invention relates to compounds that inhibit VEGF receptor tyrosine kinases, especially KDR, pharmaceutical compositions that contain such compounds, methods of treating VEGF receptor kinase-dependent diseases and conditions in mammals using such compounds and composition and methods for their manufacture.

Porphyrins with four azole substituents in meso positions: X-ray crystal structure of meso-tetrakis-(1-benzylpyrazol-4-yl)-porphyrin at 200 K

Several new porphyrins have been prepared in improved yields using an established method which was adapted to formylpyrazoles bearing on the pyrazole N1-nitrogen protective groups. The deprotection of N-para-methoxybenzyl and SEM protected meso

Research in the Azole Series. Synthesis and 13C NMR Study of Pyrazole-4-carboxaldehydes

Ten new pyrazoles have been prepared and their 13C nmr chemical shifts compared with those of twelve other pyrazoles, some of them prepared purposely for this study.The chemical shifts are discussed statistically assuming that they are additive.A formyl group in the position 4 of the pyrazole ring produces a large effect on carbon C4 (SCS = 17.3 ppm) and medium effects on carbons C3 (SCS = 1.9 ppm) and C5 (SCS = 3.8 ppm).The azines derived from pyrazole-4-carboxaldehydes are of the E,E-configuration.