153718-75-3

Upstream product

• 153718-74-2 Toluene-4-sulfonic acid 2-[4-amino-6,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl ester 
• 153718-72-0 1-N-(p-tolylsulfonyl)-3-<2-p-<(tolylsulfonyl)oxy>ethyl>-4-nitro-6,7-dimethoxyindole 
• 153718-68-4 Toluene-4-sulfonic acid 2-[6,7-dimethoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl ester 
• 184957-87-7 7,8-Dimethoxy-3,4-dihydro-1H-pyrrolo[4,3,2-de]quinoline-5-carboxylic acid tert-butyl ester 
• 184957-78-6 4-(dimethoxymethyl)-6,7-dimethoxy-5-nitroquinoline 
• 184957-81-1 5-amino-1,2,3,4-tetrahydro-6,7-dimethoxy-4-(dimethoxymethyl)quinoline 
• 6315-89-5 3,4-dimethoxyaniline 
• 159394-51-1 4-formyl-6,7-dimethoxy-5-nitroquinoline 
• 159394-50-0 6,7-dimethoxy-4-methyl-5-nitroquinoline 
• 184957-85-5 1,3,4,5-tetrahydro-7,8-dimethoxypyrrolo<4,3,2-de>quinoline 
• 105908-35-8 6,7-dimethoxy-4-methylquinoline 
• 184957-88-8 7,8-Dimethoxy-1-(toluene-4-sulfonyl)-3,4-dihydro-1H-pyrrolo[4,3,2-de]quinoline-5-carboxylic acid tert-butyl ester 

Downstream Products

• 153718-76-4 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one 

Relevant academic research and scientific papers

Synthesis of pyrrolo[4,3,2-de]quinolines from 6,7-dimethoxy-4-methylquinoline. Formal total syntheses of damirones A and B, batzelline C, isobatzelline C, discorhabdin C, and makaluvamines A-D

2-Amino-4-nitrophenol and 2-methoxy-5-nitroaniline were converted into the 5-nitroquinolines 6b and 6d, respectively, and then the latter into nitro-acetal 6f. 6,7-Dimethoxy-4-methylquinoline (6g) was nitrated at C-5 and then the methyl substituent conver

Synthetic studies of the pyrroloquinoline nucleus of the makaluvamine alkaloids. Synthesis of the topoisomerase II inhibitor makaluvamine D

A new synthesis of the pyrrolo[4,3,2-de]quinoline system characteristic of a class of marine alkaloids which includes the prianosins, discorhabdins, and other antineoplastic agents has been developed. The approach is exemplified in a total synthesis of ma