153758-85-1

Basic information

• Product Name: isopropyl 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate
• Synonyms: isopropyl 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate
• CAS NO: 153758-85-1
• Molecular Weight: 403.906
• Mol File: 153758-85-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: isopropyl 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: isopropyl 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate(153758-85-1)
• EPA Substance Registry System: isopropyl 2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate(153758-85-1)

Safety Data

• Hazardous Substances Data: 153758-85-1(Hazardous Substances Data)

Upstream product

• 51368-55-9 isopropyl 2-bromo-2?methylpropanoate 
• 41859-57-8 4-chloro-N-(4-hydroxyphenethyl)benzamide 
• 51-67-2 tyrosamine 

Downstream Products

• 41859-67-0 bezafibrate 

Relevant articles and documents

Amide Bond Formation via the Rearrangement of Nitrile Imines Derived from N-2-Nitrophenyl Hydrazonyl Bromides

We report how the rearrangement of highly reactive nitrile imines derived from N-2-nitrophenyl hydrazonyl bromides can be harnessed for the facile construction of amide bonds. This amidation reaction was found to be widely applicable to the synthesis of primary, secondary, and tertiary amides and was used as the key step in the synthesis of the lipid-lowering agent bezafibrate. The orthogonality and functional group tolerance of this approach was exemplified by the N-acylation of unprotected amino acids.